Evaluation of the protection of commercial live and inactivated NDV vaccines against Newcastle virus genotype VIId circulating in the field

Document Type : Original Article

Authors

1 Department of Poultry Diseases, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt

2 Animal Health Research Institute, National Lab. of Vet. Quality Control on Poultry Production (NLQP), Dokki, Giza, Egypt

3 Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Egypt

4 Public Authority of Veterinary Medical Services, El-Behera Adminstrator, Damanhour, El-Behera, Egypt

Abstract

The most prevalently circulating genotype of Newcastle disease (NDV)
in Egypt was VII of class II NDV strains. Control of NDV by vaccination
is a common strategy in intensively raised commercial flocks and
Newcastle disease vaccines have been used worldwide to protect against
clinical signs and mortalities. The aim of the present study was to evaluate
the level of protection against clinical disease and virus shedding afforded
by different NDV vaccines. The strain used for challenge was
NDV/CH/EG/18/2015 (GenBank accession number- KU377781),
classified as Genotype VIId with ICPI of 1.89, and MDT of 48 hrs. Broiler
chickens were challenged intra-occularily at 28 days of age using 100 μl of
106 EID50 per dose/bird. Results indicated that protection percent against
mortality and clinical signs was 100 % and 93.3 % for inactivated NDV
vaccine and LaSota, respectively. Shedding was not prevented by any
vaccine.

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